Plant Transcription Factor Database
Previous version: v3.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT2G25900.2
Common NameATCTH, ATTZF1, F17H15.7
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family C3H
Protein Properties Length: 315aa    MW: 35464.7 Da    PI: 7.434
Description C3H family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT2G25900.2genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
                  --SGGGGTS--TTTTT-SS-SS CS
      zf-CCCH   5 lCrffartGtCkyGdrCkFaHg 26 
                   C+ f++ G C++Gd+C F+Hg
                  7******.*************9 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM003561.3E-5130156IPR000571Zinc finger, CCCH-type
PROSITE profilePS5010313.469131157IPR000571Zinc finger, CCCH-type
PfamPF006421.8E-6135155IPR000571Zinc finger, CCCH-type
Gene3DG3DSA:4.10.1000.104.2E-4135157IPR000571Zinc finger, CCCH-type
PROSITE profilePS501036.296165189IPR000571Zinc finger, CCCH-type
SMARTSM0035627165188IPR000571Zinc finger, CCCH-type
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0061157Biological ProcessmRNA destabilization
GO:0005737Cellular Componentcytoplasm
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0003727Molecular Functionsingle-stranded RNA binding
GO:0046872Molecular Functionmetal ion binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000013anatomycauline leaf
PO:0000025anatomyroot tip
PO:0000037anatomyshoot apex
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009025anatomyvascular leaf
PO:0009052anatomyflower pedicel
PO:0020003anatomyplant ovule
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 315 aa     Download sequence    Send to blast
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.239160.0bud| cell culture| flower| seed| silique| vegetative tissue
Expression -- Microarray ? help Back to Top
Source ID E-value
Expression AtlasAT2G25900-
Functional Description ? help Back to Top
Source Description
TAIRputative Cys3His zinc finger protein (ATCTH) mRNA, complete
Function -- GeneRIF ? help Back to Top
  1. This study suggested that, Since TZF1 can bind both DNA and RNA in vitro, it raises the possibility that TZF1 might be involved in DNA and/or RNA regulation.
    [PMID: 19897605]
  2. AtTZF1 may serve as a regulator connecting sugar, ABA, GA and peptide hormone responses.
    [PMID: 21223390]
  3. AtTZF1 fusion proteins could not exert obvious transcriptional activity in a maize protoplast transient expression system.
    [PMID: 21455027]
  4. AtTZF1 triggers the decay of AU-rich elements-containing mRNAs.TFZ1 protein zinc finger integrity is vital for RNA binding.
    [PMID: 24635033]
  5. Overexpression of AtZFP1 enhances salt tolerance by maintaining ionic balance and limiting oxidative and osmotic stress.
    [PMID: 25074582]
Cis-element ? help Back to Top
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT2G25900
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAC0053950.0AC005395.3 Arabidopsis thaliana chromosome 2 clone F17H15 map B68, complete sequence.
GenBankAF3705900.0AF370590.1 Arabidopsis thaliana putative CCCH-type zinc finger protein (At2g25900; F17H15.7) mRNA, complete cds.
GenBankAF3754030.0AF375403.1 Arabidopsis thaliana At2g25900/F17H15.7 mRNA, complete cds.
GenBankAK1172720.0AK117272.1 Arabidopsis thaliana At2g25900 mRNA for putative Cys3His zinc finger protein ATCTH (ATCTH), complete cds, clone: RAFL16-82-I02.
GenBankAY1294680.0AY129468.1 Arabidopsis thaliana At2g25900/F17H15.7 mRNA, complete cds.
GenBankCP0026850.0CP002685.1 Arabidopsis thaliana chromosome 2, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001189604.10.0putative Cys3His zinc finger protein ATCTH
RefseqNP_180161.10.0putative Cys3His zinc finger protein ATCTH
SwissprotO823070.0C3H23_ARATH; Zinc finger CCCH domain-containing protein 23
TrEMBLD7LC090.0D7LC09_ARALL; Putative uncharacterized protein
STRINGAT2G25900.10.0(Arabidopsis thaliana)
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
  2. Seki M, et al.
    Functional annotation of a full-length Arabidopsis cDNA collection.
    Science, 2002. 296(5565): p. 141-5
  3. Cartieaux F, et al.
    Transcriptome analysis of Arabidopsis colonized by a plant-growth promoting rhizobacterium reveals a general effect on disease resistance.
    Plant J., 2003. 36(2): p. 177-88
  4. Yamada K, et al.
    Empirical analysis of transcriptional activity in the Arabidopsis genome.
    Science, 2003. 302(5646): p. 842-6
  5. Kasukabe Y, et al.
    Overexpression of spermidine synthase enhances tolerance to multiple environmental stresses and up-regulates the expression of various stress-regulated genes in transgenic Arabidopsis thaliana.
    Plant Cell Physiol., 2004. 45(6): p. 712-22
  6. Contento AL,Kim SJ,Bassham DC
    Transcriptome profiling of the response of Arabidopsis suspension culture cells to Suc starvation.
    Plant Physiol., 2004. 135(4): p. 2330-47
  7. Tran RK, et al.
    Chromatin and siRNA pathways cooperate to maintain DNA methylation of small transposable elements in Arabidopsis.
    Genome Biol., 2005. 6(11): p. R90
  8. Coupe SA, et al.
    Systemic signalling of environmental cues in Arabidopsis leaves.
    J. Exp. Bot., 2006. 57(2): p. 329-41
  9. Delaney KJ, et al.
    Calmodulin interacts with and regulates the RNA-binding activity of an Arabidopsis polyadenylation factor subunit.
    Plant Physiol., 2006. 140(4): p. 1507-21
  10. Diet A, et al.
    The Arabidopsis root hair cell wall formation mutant lrx1 is suppressed by mutations in the RHM1 gene encoding a UDP-L-rhamnose synthase.
    Plant Cell, 2006. 18(7): p. 1630-41
  11. Little D,Gouhier-Darimont C,Bruessow F,Reymond P
    Oviposition by pierid butterflies triggers defense responses in Arabidopsis.
    Plant Physiol., 2007. 143(2): p. 784-800
  12. Osuna D, et al.
    Temporal responses of transcripts, enzyme activities and metabolites after adding sucrose to carbon-deprived Arabidopsis seedlings.
    Plant J., 2007. 49(3): p. 463-91
  13. Alves-Ferreira M, et al.
    Global expression profiling applied to the analysis of Arabidopsis stamen development.
    Plant Physiol., 2007. 145(3): p. 747-62
  14. Wang D, et al.
    Genome-wide analysis of CCCH zinc finger family in Arabidopsis and rice.
    BMC Genomics, 2008. 9: p. 44
  15. Soitamo AJ,Piippo M,Allahverdiyeva Y,Battchikova N,Aro EM
    Light has a specific role in modulating Arabidopsis gene expression at low temperature.
    BMC Plant Biol., 2008. 8: p. 13
  16. Usadel B, et al.
    Global transcript levels respond to small changes of the carbon status during progressive exhaustion of carbohydrates in Arabidopsis rosettes.
    Plant Physiol., 2008. 146(4): p. 1834-61
  17. Ascencio-Ib
    Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.
    Plant Physiol., 2008. 148(1): p. 436-54
  18. Skinner DJ,Gasser CS
    Expression-based discovery of candidate ovule development regulators through transcriptional profiling of ovule mutants.
    BMC Plant Biol., 2009. 9: p. 29
  19. Pomeranz MC, et al.
    The Arabidopsis tandem zinc finger protein AtTZF1 traffics between the nucleus and cytoplasmic foci and binds both DNA and RNA.
    Plant Physiol., 2010. 152(1): p. 151-65
  20. Pomeranz M,Lin PC,Finer J,Jang JC
    AtTZF gene family localizes to cytoplasmic foci.
    Plant Signal Behav, 2010. 5(2): p. 190-2
  21. Lin PC, et al.
    The Arabidopsis tandem zinc finger protein AtTZF1 affects ABA- and GA-mediated growth, stress and gene expression responses.
    Plant J., 2011. 65(2): p. 253-68
  22. Pomeranz M,Zhang L,Finer J,Jang JC
    Can AtTZF1 act as a transcriptional activator or repressor in plants?
    Plant Signal Behav, 2011. 6(5): p. 719-22
  23. Bogamuwa S,Jang JC
    The Arabidopsis tandem CCCH zinc finger proteins AtTZF4, 5 and 6 are involved in light-, abscisic acid- and gibberellic acid-mediated regulation of seed germination.
    Plant Cell Environ., 2013. 36(8): p. 1507-19
  24. Qu J,Kang SG,Wang W,Musier-Forsyth K,Jang JC
    The Arabidopsis thaliana tandem zinc finger 1 (AtTZF1) protein in RNA binding and decay.
    Plant J., 2014. 78(3): p. 452-67
  25. Han G, et al.
    The CCCH zinc finger protein gene AtZFP1 improves salt resistance in Arabidopsis thaliana.
    Plant Mol. Biol., 2014. 86(3): p. 237-53